In the journey towards the spiritual goal, who can a seeker rely on, and what personal qualities are necessary?

Chapter 45 emphasizes self-reliance on the spiritual path. It states that worldly relations like mothers, fathers, sons, and wives cannot be fully relied upon as companions in the spiritual goal, as they are bound by their own affections and interests. Upon final reflection, only one's own self remains at the end. Therefore, a seeker must give up hope in others and maintain strong self-confidence. The text describes a blessed seeker of liberation as one who practices discrimination between the eternal and transient, renounces the fruits of enjoyment, and achieves the six-fold virtues such as calmness and self-control. Only such a person who girds up their own loins will achieve the spiritual goal.