If worldly relationships can't help in the spiritual goal, what does the text say a seeker must do to achieve liberation?

Chapter 45 clearly states that worldly relations like parents, spouses, or children are not reliable companions for achieving the spiritual goal. Instead, a blessed seeker of liberation must ultimately rely on their own self. The text advises that such a person should give up hope in others, maintain strong self-confidence, and gird up their own loins. The path involves practicing discrimination between the eternal and the transient, renouncing the fruits of enjoyment in this world and the next, and achieving the six-fold virtues, which include calmness and self-control.