According to the teachings in Chapter 45, how can a seeker achieve their ultimate spiritual goal, especially when worldly relationships prove unreliable?

Chapter 45 advises that a seeker must cultivate self-reliance to achieve their spiritual goal, as worldly relations are not dependable companions on this path. The text observes that family members like mothers, fathers, sons, and wives have affections tied to worldly concerns and cannot assist in the ultimate spiritual quest. Therefore, the seeker must realize that, in the end, only their own self remains. The process for achieving the goal, as outlined in this chapter, involves practicing discrimination between the eternal (Brahman) and the transient (the world), renouncing the fruits of enjoyment, and achieving virtues like calmness and self-control. One must give up hope in others and maintain strong self-confidence to succeed.